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PubMed COVID-19 Clinical Care

30351 - 30360 of 44979 results found

Solvated interaction energy: from small-molecule to antibody drug design

Date
Friday, June 23, 2023 - 4:00 AM
Description
Scoring functions are ubiquitous in structure-based drug design as an aid to predicting binding modes and estimating binding affinities. Ideally, a scoring function should be broadly applicable, obviating the need to recalibrate and refit its

Endemic oscillations for SARS-CoV-2 Omicron-A SIRS model analysis

Date
Friday, June 23, 2023 - 4:00 AM
Description
The SIRS model with constant vaccination and immunity waning rates is well known to show a transition from a disease-free to an endemic equilibrium as the basic reproduction number r0 is raised above threshold. It is shown that this model maps to

Subacute Thyroiditis Complicating COVID-19 Infection

Date
Friday, June 23, 2023 - 4:00 AM
Description
Subacute thyroiditis (SAT) is a self-limited inflammatory disease and a rare cause of thyrotoxicosis. Although the exact etiology of SAT is not sufficiently understood, it is generally associated to viral infections. Current evidence highlights that

Effect of weight-adjusted intermediate-dose versus fixed-dose prophylactic anticoagulation with low-molecular-weight heparin on venous thromboembolism among noncritically and critically ill patients with COVID-19: the COVI-DOSE trial, a multicenter, ra...

Date
Friday, June 23, 2023 - 4:00 AM
Description
BACKGROUND: Venous thromboembolism is a major complication of coronavirus disease 2019 (COVID-19). We hypothesized that a weight-adjusted intermediate dose of anticoagulation may decrease the risk of venous thromboembolism COVID-19 patients.