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PubMed COVID-19 Clinical Care

3811 - 3820 of 44979 results found

Docking and other computing tools in drug design against SARS-CoV-2

Date
Wednesday, February 14, 2024 - 4:00 AM
Description
The use of computer simulation methods has become an indispensable component in identifying drugs against the SARS-CoV-2 coronavirus. There is a huge body of literature on application of molecular modelling to predict inhibitors against target

A general platform for targeting MHC-II antigens via a single loop

Date
Wednesday, February 14, 2024 - 4:00 AM
Description
Class-II major histocompatibility complexes (MHC-IIs) are central to the communications between CD4+ T cells and antigen presenting cells (APCs), but intrinsic structural features associated with MHC-II make it difficult to develop a general

Standardization of the protocol for oral cavity examination and collecting of the biological samples for microbiome research using the next-generation sequencing (NGS): own experience with the COVID-19 patients

Date
Wednesday, February 14, 2024 - 4:00 AM
Description
To date, publications have shown that compositions of oral microbiota differ depending on their habitats (e.g. tongue, tonsils, pharynx). The absence of set standards for the choice of the areas and conditions of material collection makes the oral